RNA Details
Disease Name
cardiomegaly
Tissue
heart
RNA Symbol
mir-29b-1
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
immunohistochemistry; immunohistochemistry etc.
Target
SMAD3
Pathway
NA
PubMed ID
Title
MiR-29b as a Therapeutic Agent for Angiotensin II-induced Cardiac Fibrosis by Targeting TGF-B/Smad3 signaling
Year
2014
Function
"Targeting the transforming growth factor (TGF)-beta1 coding sequence region, thereby inhibiting TGF-beta/smad3 signaling, could be a new mechanism by which miR-29b inhibited angii-induced cardiac fibrosis."